论文部分内容阅读
目的本研究通过测定不明原因不孕症患者血清中的甲状腺自身抗体(TG-Ab、TPO-Ab),与正常健康女性做比较,用以探讨甲状腺自身抗体与不明原因不孕症的关系,为寻找不明原因不孕症的病因提供理论依据。方法用化学发光免疫分析仪测定对照组与研究组血清中的TG-Ab、TPO-Ab水平,统计其阳性率,探讨甲状腺自身抗体与不明原因不孕症的关系。结果研究组血清中ATA阳性率为27.78%,明显高于对照组(χ~2=7.98,P<0.01);TG-Ab阳性率为18.89%,与对照组相比有明显差异(χ~2=7.457,P<0.01),TPO-Ab阳性率为26.67%,明显高于对照组(χ~2=11.262,P<0.01)。结论 ATA阳性与不明原因不孕症存在一定的相关性。
ObjectiveTo study the relationship between thyroid autoantibodies and unexplained infertility by measuring thyroid autoantibodies (TG-Ab, TPO-Ab) in serum of unexplained infertility patients and comparing with normal healthy women To find the cause of unexplained infertility provide a theoretical basis. Methods The levels of TG-Ab and TPO-Ab in the serum of the control group and the study group were determined by chemiluminescence immunoassay and the positive rate was calculated. The relationship between thyroid autoantibodies and unexplained infertility was discussed. Results The positive rate of ATA in the study group was 27.78%, which was significantly higher than that in the control group (χ ~ 2 = 7.98, P <0.01). The positive rate of TG-Ab in the study group was 18.89% = 7.457, P <0.01). The positive rate of TPO-Ab was 26.67%, which was significantly higher than that of the control group (χ ~ 2 = 11.262, P <0.01). Conclusion ATA positive and unexplained infertility there is a certain correlation.