目的:分析大肠侧向发育型肿瘤(LST)内镜下综合诊治临床疗效及体会。方法:收集2015年8月至2017年1月在东莞市人民医院治疗的69例LST患者资料,根据患者肿瘤情况给予其内镜黏膜切除术(EMR)、黏膜剥离术(ESD)、分片切除术(EPMR)治疗,分析3种手术治疗效果。结果:超声内镜(EUS)检出混合结节型17例、颗粒均一型27例、扁平隆起25例;病灶直径为10~50 mm,分布于黏膜层49例、下层黏膜受累20例;手术:外科手术7例、EMR 20例、ESD 19例、EPMR 23例,切除完整率76.81%,并发症率13.04%,复发率10.13%。结论:以内镜下EMR、ESD、EPMR术式治疗LST疾病均有良好效果,其中,ESD病灶清除较彻底,复发率低,应用价值良好。 Objective: To analyze the clinical effect and experience of endoscopic diagnosis and treatment of colorectal growth type tumor (LST). Methods: The data of 69 patients with LST treated in Dongguan People’s Hospital from August 2015 to January 2017 were collected. According to the tumor status, patients underwent endoscopic mucosal resection (EMR), mucosal dissection (ESD) and segmented resection (EPMR) treatment, analysis of three kinds of surgical treatment. Results: 17 cases of mixed nodules were detected by EUS, 27 cases were uniform type and 25 cases were flat bulge. The diameter of lesion ranged from 10 to 50 mm, distributed in 49 cases of mucosa and 20 cases of mucosa in the lower. There were 7 cases of surgery, 20 cases of EMR, 19 cases of ESD and 23 cases of EPMR. The complete resection rate was 76.81%, the complication rate was 13.04% and the recurrence rate was 10.13%. Conclusion: Endoscopic EMR, ESD, EPMR surgical treatment of LST disease have good results, of which, ESD lesions cleared more thoroughly, the recurrence rate is low, the application value is good.