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目的:分析定量CT在腰椎各椎体间骨密度测量中的差异性,探讨骨密度测量有效措施。方法:选择我科收治的286例临床需要进行BMD测量患者,对其进行DXA和QCT测量,比较与分析两种测量方法的有效性。结果:QCT测量男、女L2、3、4椎体的BMD含量不等,但差异无统计学意义(P>0.05),且无论男性、女性,各椎体间BMD含量差异亦无统计学意义(P>0.05)。DXA测量男、女L2、3、4椎体的BMD含量不等,但各椎体间BMD含量具统计学意义(P<0.05),且随着椎体的增加,BMD含量呈现增加的趋势。结论:相较于DXA而言,QCT能更准确地进行骨密度测量,更适于临床应用。
OBJECTIVE: To analyze the difference of quantitative bone mineral density measurement between lumbar vertebrae by quantitative CT, and to explore effective measures of bone mineral density measurement. Methods: A total of 286 patients with BMD were enrolled in our department. DXA and QCT were performed to compare and analyze the validity of the two measurement methods. Results: There was no significant difference in the BMD content between male and female L2,3,4 vertebrae by QCT (P> 0.05), and there was no significant difference in BMD content between male, female and vertebral bodies (P> 0.05). The BMD content of L2,3,4 vertebral bodies in male and female were different with DXA, but the BMD content in each vertebral body was statistically significant (P <0.05). With the increase of vertebral body, BMD content showed an increasing tendency. Conclusion: Compared with DXA, QCT can measure bone mineral density more accurately and is more suitable for clinical application.