非何杰金恶性淋巴瘤是一组对化疗敏感的肿瘤 ,某些病理类型经过化疗可以达到治愈 ,但有部分患者缓解后仍会复发 ,并有少数患者对以往有效的药物不再敏感 ,产生耐药性 ,即所谓难治性淋巴瘤。要使这些患者再获缓解并长期生存 ,往往需要更加强烈的方案化疗以及造血干细胞移植保护 Non-Hodgkin’s malignant lymphoma is a group of chemotherapy-sensitive tumors, some of the pathological types of chemotherapy can be cured, but some patients will relapse after remission, and a small number of patients on the past effective drug is no longer sensitive to produce Drug resistance, the so-called refractory lymphoma. For these patients to remission and long-term survival, more intensive chemotherapy and hematopoietic stem cell transplantation are often needed