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烟硷与烟硷受体结合能产生镇痛作用，但其镇痛作用较局限，并有许多副作用。Ｅｐｉｂａｔｉｄｉｎｅ是从厄瓜多尔一种蛙的皮肤中提取的化合物，能与中枢神经元烟硷受体结合，产生强而广泛的镇痛作用。但ｅｐｉｂａｔｉｄｉｎｅ还能与交感神经节和神经肌肉接头处的烟硷受体...
Nicotine and nicotinic acid receptor can produce analgesic effect, but its analgesic effect is more limited and has many side effects. Epibatidine, a compound extracted from the skin of a frog in Ecuador, binds to central neuronal nicotinic receptors and produces a strong and widespread analgesic effect. But epibatidine also works with sympathetic ganglia and neuromuscular junction nicotinic receptors ...