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目的探讨平阳霉素联合普萘洛尔治疗婴幼儿头面部血管瘤的临床疗效。方法将我院婴幼儿头面部血管瘤患儿67例随机分为观察组34例和对照组33例,观察组采用平阳霉素联合普萘洛尔治疗,对照组仅采用平阳霉素治疗,3月后对比疗效,并观察不良反应。结果观察组总体疗效优于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为20.6%,略高于对照组的9.1%,差异无统计学意义(P>0.05)。结论平阳霉素联合普萘洛尔治疗婴幼儿头面部血管瘤疗效确切,且不良反应较轻微,是临床治疗本病的新途径。
Objective To investigate the clinical efficacy of bleomycin combined with propranolol in the treatment of infantile head and facial hemangiomas. Methods 67 cases of infantile head and facial hemangiomas in our hospital were randomly divided into observation group of 34 cases and control group of 33 cases. The observation group was treated with pingyangmycin combined with propranolol, while the control group was treated with pingyangmycin only. 3 Month after the comparison of efficacy, and observed adverse reactions. Results The overall curative effect of the observation group was better than that of the control group (P <0.05). The incidence of adverse reactions in the observation group was 20.6%, slightly higher than that of the control group (9.1%), with no significant difference (P> 0.05) . Conclusion Pingyangmycin combined with propranolol in the treatment of infantile head and facial hemangioma has definite curative effect and mild adverse reactions, which is a new way of clinical treatment of this disease.