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目的:评价生物胶联合OK-432和平阳霉素治疗面颈部巨大静脉畸形的临床疗效。方法:26例面颈部巨大静脉畸形患者,男11例,女15例;年龄4～23岁,平均年龄11.8岁。通过注射生物胶联合OK-432和平阳霉素进行治疗。所有病例均只接受1次治疗。结果:除术区2～3周肿胀外,均无严重并发症出现。随诊6～12个月(平均8.4个月),19例治愈,5例显效,2例有效,无无效病例。结论:生物胶联合OK-432和平阳霉素经皮硬化术治疗面颈部巨大静脉畸形,效果良好,并且简单、安全和可靠。
OBJECTIVE: To evaluate the clinical efficacy of bio-gum combined with OK-432 and pingyangmycin in treating giant venous malformations of face and neck. Methods: Twenty-six patients with giant venous malformations of face and neck were enrolled in this study. There were 11 males and 15 females, aged from 4 to 23 years with a mean age of 11.8 years. Treatment with OK-432 and pingyangmycin was performed by injection of bio-gel. All cases received only 1 treatment. Results: In addition to the swelling area of 2 to 3 weeks, no serious complications occurred. Followed up for 6 to 12 months (average 8.4 months), 19 cases were cured, 5 cases markedly effective, 2 cases effective, no ineffective cases. Conclusion: The combination of bio-gel and OK-432 and pingyangmycin in the treatment of giant facial venous malformations is effective, simple, safe and reliable.