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目的:探讨洛伐他汀联合灯盏花素治疗糖尿病足(DF)临床疗效。方法:将入选病例随机分为对照组(32例)和治疗组(31例),对照组给予前列腺E1静滴,治疗组给予洛伐他汀片口服,灯盏花素静滴,连续治疗4周。结果:治疗组治愈21例(67.7%),有效6例(19.4%),无效4例(12.9%),总效率为87.1%;对照组治愈7例(21.9%),有效20例(62.5%),无效6例(15.6%),总效率84.4%,两组总疗效比较差异无统计学意义(P>0.05),治愈率差异有统计学意义(P<0.01)。结论:洛伐他汀联合灯盏花素对DF的治愈有较好的临床疗效。
Objective: To investigate the clinical efficacy of lovastatin and breviscapine in the treatment of diabetic foot (DF). Methods: The selected cases were randomly divided into control group (n = 32) and treatment group (n = 31). The control group received prostatic E1 infusion. The treatment group received lovastatin tablet orally and breviscapine infusion for 4 weeks. Results: The treatment group cured 21 cases (67.7%), effective 6 cases (19.4%), ineffective 4 cases (12.9%), total efficiency 87.1%; control group 7 cases (21.9% ), 6 cases (15.6%) were ineffective, and the total efficiency was 84.4%. There was no significant difference in the total curative effect between the two groups (P> 0.05). The cure rate had statistical significance (P <0.01). Conclusion: Lovastatin combined with Breviscapine has a good clinical effect on the cure of DF.