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[目的]调查职业性噪声致双耳高频听损人群的心血管疾病相关指标。[方法]以某火力发电厂工人为研究对象,排除有心脑血管、肝、肾等重大疾病史,高血压、糖尿病、冠心病家族史及酗酒史,研究对象共126例。按双耳高频听阈分为对照组[≤25dB(HL),64例]、轻度损伤组[26~40dB(HL),39例]、重度损伤组[≥41dB(HL),23例]。分析每组人员的空腹血糖、血胆固醇、血三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇含量及高血压患病率、ST段压低阳性率。[结果]随双耳高频听阈增加,各组间血胆固醇、空腹血糖含量及高血压患病率、ST段压低阳性率呈增高趋势(P<0.05)。轻度、重度损伤组中血三酰甘油明显高于对照组(P<0.05)。高密度脂蛋白胆固醇、低密度脂蛋白胆固醇在各组间差异无统计学意义(P>0.05)。[结论]双耳高频听阈损伤可能与某些心血管疾病相关指标存在不同程度的相互作用,保护噪声从业人员听力可能是降低心血管疾病危险因素的职业措施。
[Objective] To investigate the cardiovascular disease-related indicators of occupational noise-induced high-frequency hearing loss in both ears. [Method] Taking a worker of a thermal power plant as the research object, 126 cases of history of major diseases such as cardiovascular and cerebrovascular diseases, liver and kidney, hypertension, diabetes mellitus, family history of coronary heart disease and alcohol abuse were excluded. According to the two-ear high-frequency hearing threshold, they were divided into control group [≤25dB (HL), 64 cases], mild injury group [26-40dB (HL), 39 cases) . The fasting blood glucose, blood cholesterol, blood triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, the prevalence of hypertension and ST-segment depression in each group were analyzed. [Results] With the increase of binaural high-frequency hearing threshold, the blood cholesterol, fasting blood glucose, prevalence of hypertension and the ST-segment depression in all groups showed an increasing trend (P <0.05). Blood triglycerides in mild and severe injury group were significantly higher than those in control group (P <0.05). High density lipoprotein cholesterol, low density lipoprotein cholesterol in all groups showed no significant difference (P> 0.05). [Conclusion] The high-frequency hearing loss in both ears may have some degree of interaction with some cardiovascular disease-related indicators. To protect the noise practitioners’ hearing ability may be an occupational measure to reduce the risk factors of cardiovascular disease.