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目的探讨血管性假血液病因子(vWF)、凝血酶原片断(F1+2)与老年性高血压之间的关系。方法用免疫浊度法测定血浆vWF的含量,用ELISA法测定血浆F1+2。结果老年性高血压患者的vWF显著高于正常对照组(P<0.01),老年性高血压患者的F1+2,显著高于正常对照组(P<0.01)。结论老年性高血压患者的内皮细胞功能有明显得损害,处于相对的高凝状态和有血栓形成的倾向。
Objective To investigate the relationship between vWF, prothrombin (F1 + 2) and senile hypertension. Methods Plasma vWF levels were determined by immunoturbidimetry and plasma levels of F1 + 2 were measured by ELISA. Results The vWF of senile hypertension patients was significantly higher than that of the normal control group (P <0.01). The F1 + 2 of senile hypertension patients was significantly higher than that of the normal control group (P <0.01). Conclusions The function of endothelial cells in elderly patients with hypertension is significantly impaired, with relative hypercoagulability and thrombosis tendency.