皮肌炎是结缔组织病之一,现多采用激素或激素加免疫抑制剂治疗,即使部分病例能获得缓解,但多留有不同程度的肌无力。我们用强的松加牛胸腺肽治疗1例小儿皮肌炎获得完全缓解,报告如下。患儿刘×,女,2.5岁。1982年5月开始低热、面部红斑。7月出现全身无力,抬头及行走困难、语声减弱,逐渐加重。于同年9月2日入我院。体检:体温37.4,哭声细微,皮肤干燥,有少量脱屑;上眼脸、鼻根部、前额及颈部皮肤均可见暗红色斑;面颊及四肢皮肤硬韧。颈肌无力,四肢肌力明显减低,不能步行。实验室检查:血常规正常,尿蛋白(+),狼疮细胞及类风湿因子阴性,蛋白电泳分析及免疫球蛋白测定均属正常,T-细胞 Dermatomyositis is one of the connective tissue diseases, hormone therapy or hormone plus immunosuppressive therapy is often used. Even if some cases can be alleviated, some muscle weakness may remain. We use prednisone plus bovine thymosin in 1 case of pediatric dermatomyositis was completely relieved, the report is as follows. Liu × children, female, 2.5 years old. May 1982 low fever, facial erythema. In July there was general weakness, rise and walking difficulties, voice weakened, and gradually increased. In September 2 the same year into our hospital. Physical examination: body temperature 37.4, subtle cries, dry skin, a small amount of scaling; on the face, nose, forehead and neck skin are visible dark red spots; cheeks and limbs, skin tough. Neck muscle weakness, limb muscle strength was significantly reduced, can not walk. Laboratory tests: normal blood, urinary protein (+), lupus cells and rheumatoid factor negative, protein electrophoresis analysis and immunoglobulin determination are normal, T-cells