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目的探讨心肌型脂肪酸结合蛋白(H-FABP)在急性心肌梗死(AMI)早期诊断的临床意义。方法选择AMI患者36例,按胸痛距采血时间检测H-FABP浓度,即为AMI组。同时将正常人70例采血检测H-FABP浓度设为正常对照组。结果正常对照组与AMI组的H-FABP浓度相比差异具有显著性[曲线下面积(AUC)为0.954,AUC<0.5时无诊断价值]。结论 H-FABP在AMI早期诊断具有重要的临床意义。
Objective To investigate the clinical significance of early detection of myocardial fatty acid binding protein (H-FABP) in acute myocardial infarction (AMI). Methods Thirty-six patients with AMI were selected, and the concentration of H-FABP was determined according to the time of collecting blood from chest pain, which was AMI group. At the same time, 70 normal blood samples were collected to detect H-FABP concentration as normal control group. Results The difference of H-FABP concentration between normal control group and AMI group was significant (area under the curve (AUC) was 0.954, no diagnostic value when AUC <0.5). Conclusion H-FABP in the early diagnosis of AMI has important clinical significance.