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对68例肝病患者检查结果发现晚期血吸虫病患者合并慢性肝炎感染率高达72.1％.肝炎后肝硬化的主要组织学改变为肝细胞变性坏死、纤维间隔及假小叶形成、小胆管增生伴上皮肿胀和淋巴细胞浸润。其中,地衣红染色阳性系乙型肝炎病毒感染的证据。HBsAg阴性而抗HBc—IgM阳性提示乙型肝炎新近感染:两者均阳性或伴HBeAg阳性提示病毒仍在复制。本文抗HBc—lgG阳性率特别高,可能是晚血患者乙型肝炎病程慢性化的结果。检测血清RF、ANA、AFP、CIC和MAO有助于鉴别诊断及对预后的判断。血脂HDL-C/T.ch比值<0.3伴肝功能动态变化者多导致肝炎后肝硬化.
The results of 68 patients with liver disease found that patients with advanced schistosomiasis chronic hepatitis infection rate as high as 72.1% .The main histological changes of liver cirrhosis were hepatocellular degeneration and necrosis, fibrocyte septum and pseudolobule formation, small bile duct hyperplasia with epithelial swelling and Lymphocyte infiltration. Among them, lichen red staining positive evidence of hepatitis B virus infection. HBsAg-negative and anti-HBc-IgM positive suggests a recent hepatitis B infection: both positive or HBeAg positive suggest that the virus is still replicating. This anti-HBc-lgG-positive rate is particularly high, may be due to chronic liver disease in patients with chronic disease results. Detection of serum RF, ANA, AFP, CIC and MAO contribute to the differential diagnosis and prognosis. Serum lipid HDL-C / T.ch ratio <0.3 with the dynamic changes in liver function and more lead to post-hepatitis cirrhosis.