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目的探讨采用无创机械通气治疗重症间质性肺疾病的临床效果。方法选取郑州市中心医院收治的重症间质性肺疾病患者48例,在常规治疗的基础上联合无创机械通气对所有患者进行治疗,并对治疗前后患者的临床体征、症状、血气改变及转归结果进行观察记录。结果在采用无创机械通气治疗24h后,患者的心率(H R)、呼吸频率(RR)、血二氧化碳分压(PaCO_2)同治疗前相比明显降低,动脉血氧分压(PaO2)、pH值同治疗前相比明显升高,差异具有显著性(P<0.05)。结论采用无创机械通气治疗重症间质性肺疾病,效果显著,有利于促进患者呼吸功能的改善,建议在临床上进一步推广。
Objective To investigate the clinical effect of noninvasive mechanical ventilation in the treatment of severe interstitial lung disease. Methods Forty-eight patients with severe interstitial lung disease admitted to Zhengzhou Central Hospital were enrolled in this study. All patients were treated with noninvasive mechanical ventilation on the basis of routine treatment. The clinical signs, symptoms, blood gas changes and prognosis were analyzed before and after treatment The results were observed and recorded. Results The HR, respiratory rate and PaCO_2 of patients treated with noninvasive mechanical ventilation were significantly lower than those before treatment, PaO2 and pH were the same Compared with before treatment, the difference was significant (P <0.05). Conclusion Non-invasive mechanical ventilation for the treatment of severe interstitial lung disease, the effect is significant, is conducive to improving the patient’s respiratory function, it is recommended to further promote the clinical.