论文部分内容阅读
目的 探讨儿童期骨生长代谢的变化规律。方法 对成都市城区 2 2 4名 3～ 15岁健康儿童的骨生化指标、腰椎骨密度及跟骨骨小梁进行了检测和分析。结果 儿童期血清钙、磷和尿钙、磷在各年龄段无统计学上的差异 (P>0 .0 5 ) ;血清碱性磷酸酶 (AL P)及骨碱性磷酸酶 (BAL P)随年龄增长而增高 ,7～ 12岁时达到高峰 ,儿童期 AL P、BAL P明显高于成人 (P<0 .0 5 )。腰椎骨密度及跟骨骨小梁随年龄增长而增加。结论 儿童期反映骨生长代谢的生化指标、骨密度、跟骨骨小梁有其自身的变化规律 ,不能以成人的指标作为判断标准 ,而应采用儿童期的骨生长代谢指标来诊断和治疗儿童骨代谢性疾病
Objective To investigate the changes of bone growth and metabolism in childhood. Methods The bone biochemical parameters, lumbar bone mineral density and calcaneal trabecular bone were detected and analyzed in 224 healthy children aged 3 ~ 15 years old in Chengdu city. Results Serum calcium, phosphorus and urinary calcium and phosphorus in childhood had no significant difference in all age groups (P> 0.05), serum ALP and BALP, Increased with age and peaked at the age of 7 to 12 years. ALP and BALP in childhood were significantly higher than those in adults (P <0.05). Lumbar bone density and calcaneal trabecular increased with age. Conclusion Biochemical indexes reflecting bone growth and metabolism in childhood, bone mineral density, and calcaneal trabecular bone have their own rules of change. Adult criteria can not be used as criteria for diagnosis. Children with bone growth and metabolism should be used to diagnose and treat children Bone metabolic diseases