栀子黄色素是我国近年开发应用的一种天然食用色素,我室曾对其进行了两个阶段的食品毒理安全性评价及三个月的亚急性毒性试验观察,认为该色素为安全的食品添加剂。但鉴于至今尚未见有关该色素胚胎毒性的报道,为保障后代的安全健康,我们对该色素进行了小鼠胎肝微核试验观察。 Gardenia yellow pigment is a kind of natural food coloring developed and applied in recent years in our country. It has been evaluated in two stages of food poisoning safety and three months of subacute toxicity test in our lab, which is considered as safe Food additives. However, in view of the fact that there is no report about the embryotoxicity of the pigment so far, in order to ensure the safety and health of the offspring, we observed the mouse fetal liver micronucleus test.