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目的探讨神经保护剂依达拉奉对急性脑梗死患者神经功能恢复的影响。方法 61例发病在3 d内的急性脑梗死患者随机分为治疗组和对照组,两组患者均用阿司匹林、血塞通治疗,治疗组加用依达拉奉30 mg治疗14 d。两组分别在治疗前、治疗后第14 d及治疗后第28 d测定患者神经功能缺损程度及日常生活活动能力。结果两组患者在治疗前和治疗后第14 d神经功能缺损程度及日常生活能力差异均无统计学意义(P>0.05)。治疗后第28 d,治疗组日常生活活动能力较对照组明显提高(P<0.01),神经功能缺损程度明显减轻(P﹤0.01)。结论依达拉奉治疗能改善急性脑梗死患者的日常生活能力,促进神经功能恢复。
Objective To investigate the effect of neuroprotective agent edaravone on the recovery of neurological function in patients with acute cerebral infarction. Methods Sixty-one patients with acute cerebral infarction within 3 days were randomly divided into treatment group and control group. Both groups were treated with aspirin and Xuesaitong. The treatment group was treated with edaravone 30 mg for 14 days. The two groups were measured before treatment, 14 d after treatment and 28 d after treatment to determine the degree of neurological deficit and daily living activity. Results There was no significant difference between the two groups in the degree of neurological deficits and the daily living ability before treatment and 14 days after treatment (P> 0.05). On the 28th day after treatment, the activities of daily living in treatment group were significantly higher than those in control group (P <0.01), and the degree of neurological deficit was significantly reduced (P <0.01). Conclusion Edaravone can improve the daily living ability of patients with acute cerebral infarction and promote the recovery of neurological function.