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目的 通过对牙周炎治疗过程中龈下菌斑内螺旋体和球菌的百分比组成的改变进行动态观察研究，为牙周炎的诊断和疗效评价提供依据。方法 选择１８ 例经门诊确诊为成人牙周炎的患者，随机分为Ａ、Ｂ、Ｃ 三组，均施以龈上洁治、龈下刮治和根面平整术。其中Ａ 组和Ｂ 组分别给予艾利克及洗必太含漱液含漱。所有患者每周复诊一次，采集龈下菌斑，进行刚果红染色，镜检计数螺旋体及球菌的百分比，同时检测患处牙龈指数（ＧＩ） 。结果 Ａ、Ｂ 组患者经治疗１ 周后，ＧＩ值变化极为显著（Ｐ＜ ０．０１） ，螺旋体的减少及球菌的增加也极具显著性（Ｐ＜ ０．０１） ，至３ 周时趋于稳定；Ｃ 组则在１ 周时ＧＩ值及菌斑组成的变化有显著性（Ｐ＜ ０．０５） ，至２ 周时变化才最为明显（Ｐ＜ ０．０１） ，４ 周时趋于稳定。结论 牙周基础治疗能明显改善临床症状，使螺旋体百分比显著降低，球菌百分比显著增加。口腔含漱液作为一种牙周炎的辅助用药，可明显改善菌斑的组成，促进正常口腔卫生环境的建立。
Objective To study the change of the percentage composition of subgingival plaque and coccus during the treatment of periodontitis and provide basis for the diagnosis and evaluation of periodontitis. Methods 18 patients diagnosed as adult periodontitis by clinic were randomly divided into three groups: A, B and C, all of which were treated with supragingival scaling, subgingival scaling and root planing. A group and B group, respectively, which were given to Eric and chlorhexidine gargle rinse. All patients were visited once a week, and subgingival plaque was collected for Congo red staining. The percentage of spirochaetes and cocci was counted microscopically and the gingival index (GI) was measured. Results After 1 week of treatment, the changes of GI value in group A and group B were extremely significant (P <0.01). The decrease of spirochetes and the increase of cocci were also significant (P <0.01) (P <0.05). The change of GI and plaque composition in group C was significant at 1 week (P <0.05), and the change was most obvious at 2 weeks (P <0.01) stable. Conclusion The basic periodontal treatment can significantly improve the clinical symptoms, so that the percentage of spirochetes was significantly reduced, the percentage of cocci increased significantly. Oral gargle as an auxiliary periodontitis medication can significantly improve the composition of plaque and promote the establishment of normal oral hygiene environment.