【摘 要】
：
目的探讨尿激酶型纤溶酶原激活物（u PA）水平变化对卵巢上皮性癌患者化疗效果评价以及预后的影响。方法选取卵巢上皮性癌患者64例为观察组,健康体检者50例为对照组,观察2组血清u
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目的探讨尿激酶型纤溶酶原激活物（u PA）水平变化对卵巢上皮性癌患者化疗效果评价以及预后的影响。方法选取卵巢上皮性癌患者64例为观察组,健康体检者50例为对照组,观察2组血清u PA水平差异,并通过COX风险模型分析影响无瘤生存时间（PFS）和总生存时间（OS）相关因素。结果观察组患者化疗前u PA含量明显高于对照组,差异有统计学意义（P〈0.01）;化疗6次后,观察组u PA含量明显低于化疗前,却明显高于对照组,差异有统计学意义（P〈0.05）。不同手术分期（Ⅰ-Ⅱ与Ⅲ-Ⅳ）、残留病灶不同直径（≥2 c
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