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胆石形成与胆汁中胆固醇的过饱和、胆固醇结晶快速成核及/或胆囊排空不全有关。本研究调查这些因素在胆囊结石复发中的意义。 材料与方法:20例胆囊结石患者在体外震波碎石和胆汁酸溶石治疗成功后,10例于12±2月内胆囊结石再次复发(复发组),另10例配对对照随访22±3月没有复发(未复发组)。 两组分别口服同位素标记的胆酸(CA)、鹅脱氧胆酸(CDCA)和脱氧胆酸(DCA)各50mg,用气液色谱分析仪——单离子分光光度计法测
Cholelithiasis is associated with supersaturation of cholesterol in bile, rapid nucleation of cholesterol crystals, and / or incomplete gallbladder emptying. This study investigated the significance of these factors in the recurrence of gallstone disease. MATERIALS AND METHODS: Twenty patients with gallstone were treated with extracorporeal shock wave lithotripsy and bile acid dissolved stone, 10 cases recurred again in 12 ± 2 months (recurrent group) and the other 10 matched controls were followed up for 22 ± 3 months No recurrence (no relapse). The two groups were orally administered with 50 mg of isotope-labeled cholic acid (CA), chenodeoxycholic acid (CDCA) and deoxycholic acid (DCA), respectively, and measured by gas chromatography-single ion spectrophotometry