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目的:评价加替沙星序贯疗法治疗下呼吸道感染的临床效果。方法:128例下呼吸道感染患者随机分为试验组和对照组,试验组(n=62)先以加替沙星针0.2g,iv.gtt,bid,3天,后改用加替沙星胶囊0.2g,po,bid,7天;对照组(n=66)以加替沙星针0.2g,iv.gtt,bid,10天。结果:两组试验总有效率分别为93.3%和94.1%,治愈率分别为74.19%和75.76%,无显著性差异(P>0.05),序贯疗法每例可节省666.2元。结论:加替沙星序贯疗法治疗下呼吸道感染具有与加替星注射液相似的临床疗效,比单用加替沙星更具成本效果,是治疗下呼吸道感染的可靠治疗方案。
Objective: To evaluate the clinical effect of sequential therapy of gatifloxacin in the treatment of lower respiratory tract infection. Methods: 128 patients with lower respiratory tract infection were randomly divided into experimental group and control group. The experimental group (n = 62) was treated with gatifloxacin 0.2 g, iv.gtt, bid for 3 days, then gatifloxacin Capsule 0.2g, po, bid, 7 days; control group (n = 66) to gatifloxacin needle 0.2g, iv.gtt, bid, 10 days. Results: The total effective rates of the two groups were 93.3% and 94.1%, respectively. The cure rates were 74.19% and 75.76% respectively. There was no significant difference (P> 0.05). The sequential therapy could save 666.2 yuan per case. Conclusion: Gatifloxacin sequential therapy for lower respiratory tract infection has similar clinical efficacy as gatifloxacin injection, more cost-effective than gatifloxacin alone, is a reliable treatment of lower respiratory tract infection.