过去,在光镜下观察较厚的切片,膜性肾病(MN)的早期病变常被忽略,而今用现代技术则易于诊断。在实验上,对免疫复合物膜外沉积的认识也有很大进展。在欧洲及北美第一世界国家,MN是成人蛋白尿患者最常见的病变之一。以往认为本病多属特发性,后来在一些患者的肾小球基膜 In the past, looking thicker sections under light microscopy, early lesions of membranous nephropathy (MN) were often overlooked, and today modern techniques are easy to diagnose. In the experiment, the understanding of extracellular deposition of immune complexes has also made great progress. In Europe and first-world North American countries, MN is one of the most common pathologies in adults with proteinuria. In the past that the disease is mostly idiopathic, and later in some patients with glomerular basement membrane