目的了解本地区人群中5种常见性传播疾病病原体的感染情况及其特点,为地区防治工作提供可靠依据。方法采用实时荧光定量PCR法对本院10 858例疑似泌尿生殖道炎症患者进行解脲脲原体(Uu)、沙眼衣原体(CT)、淋病奈瑟菌(NG)、人乳头瘤病毒(HPV6,11)和单纯疱疹病毒(HSV-Ⅱ)等病原体的DNA定量检测,并进行统计分析。结果STD总阳性率为29.5%(3206/10858),病原体Uu、CT、NG、HPV6,11、HSV-Ⅱ阳性率分别为50.2%、12.1%、3.67%、5.68%、16.4%。男性、女性阳性率分别为22.9%、31.1%,差异有统计学意义(P<0.01)。20~40岁年龄段为主要感染人群,占86.68%。我区以Uu、CT流行为主,与其他地区存在差异。混合感染的总检出率为3.04%。结论本地区人群存在不同程度的5种性病病原体感染,加强泌尿生殖道炎症患者STD病原体的监测,对减少STD的流行与扩散具有重要意义。 Objective To understand the infection status and characteristics of five common sexually transmitted pathogens in local population and provide a reliable basis for regional prevention and treatment. Methods A total of 10 858 patients with suspected genitourinary tract inflammation were treated with real-time fluorescence quantitative PCR for Uu, CT, Neisseria gonorrhoeae (NG), human papillomavirus (HPV6, 11) and herpes simplex virus (HSV-Ⅱ) and other pathogens DNA quantitative detection, and statistical analysis. Results The positive rate of STD was 29.5% (3206/10858). The positive rates of Uu, CT, NG, HPV6, 11 and HSV-Ⅱ were 50.2%, 12.1%, 3.67%, 5.68% and 16.4% respectively. The positive rates of males and females were 22.9% and 31.1%, respectively, with significant differences (P <0.01). 20 to 40 age group as the main infection, accounting for 86.68%. My area to Uu, CT epidemic-based, there are differences with other regions. The overall detection rate of mixed infection was 3.04%. Conclusion There are five kinds of STDs in different degrees in local population. It is important to strengthen the monitoring of STD pathogens in patients with genitourinary tract inflammation and reduce the prevalence and spread of STD.