人体恶性肿瘤的浸润与转移能力是它们的一个至为重要的特征。然而,虽有许多人体肿瘤已成功地转移到遗传上无胸腺的(nude)和遗传上无脾-无胸腺的(Lasat)小鼠体内,但实际上尽管人体恶性肿瘤可在裸鼠体内活跃地增殖,肿瘤转移的发生率却极低。因此,对于免疫生物学的研究来说,人体恶性肿瘤的可重复性动物转移模型,无 The invasive and metastatic ability of human malignant tumors is one of their most important features. However, despite the fact that many human tumors have been successfully transferred to genetically ade (nude) and genetically non-spleen-athymic (Lasat) mice, in fact, despite the fact that human malignant tumors can be actively activated in nude mice, The incidence of proliferation and tumor metastasis is extremely low. Therefore, for the study of immunobiology, the reproducible animal metastasis model of human malignancy, no