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目的探讨CT与MRI图像融合技术在原发性肝癌三维适形放疗靶区确定中的应用,以供临床参考。方法对2010年1月至2011年7月收治的15例原发性肝癌的患者进行本次实验。于患者深吸气末进行CT扫描、呼气末进行MRIT2扫描和吸气末屏气时MRIT2F扫描。使用信息法对两者图像进行融合。使用骨性标记点距离与肝脏交叠度对图像融合的精度进行评价。结果使用CT与MRIT2融合与CT与MRIT2F融合对图像距离测量无差异,对肝脏交界程度测量有差异,P<0.05。两者融合后形成的总体积有明显差异,P>0.05,差异有统计学意义。结论使用CT与MRI图像融合技术在原发性肝癌三维适形放疗靶区确定具有较好的价值,其能够减少对周围器官的影响。
Objective To explore the application of CT and MRI image fusion in the determination of three-dimensional conformal radiotherapy target area of primary liver cancer for clinical reference. Methods Fifteen patients with primary liver cancer who were admitted between January 2010 and July 2011 were enrolled in this study. At the end of the patient’s deep inspiration, a CT scan was performed, with MRIT2F scanning at the end of expiration and MRIT2F scanning at the end of inspiration. Using information method to fuse the two images. The accuracy of image fusion was evaluated using the distance between bone markers and liver overlap. Results The fusion of CT and MRIT2 with CT and MRIT2F did not show any significant difference in image distance measurement, but there was significant difference in the measurement of liver junction (P <0.05). The total volume formed after fusion was significantly different, P> 0.05, the difference was statistically significant. Conclusion The use of CT and MRI image fusion techniques in the determination of three-dimensional conformal radiotherapy target area of primary liver cancer has a good value, which can reduce the impact on the surrounding organs.