潜伏性结核感染患者是结核病防治的关键人群,但目前缺乏诊断潜伏性结核感染的金标准。现有的诊断方法无法鉴别潜伏性结核和活动性结核,因此,需要建立更高效准确的方法来提高潜伏性结核的诊断准确性。近年来,一些潜伏性结核感染相关抗原被用于建立新的潜伏性结核诊断方法,本文就潜伏性结核诊断抗原的研究进展进行综述。 Patients with latent TB infection are a keystay of tuberculosis control but currently lack the gold standard for diagnosis of latent TB infection. The existing diagnostic methods can not distinguish between latent tuberculosis and active tuberculosis, therefore, there is a need to establish a more efficient and accurate method to improve the diagnostic accuracy of latent tuberculosis. In recent years, some latent tuberculosis infection-related antigens have been used to establish a new diagnostic method for latent tuberculosis. In this review, we review the progress in the diagnosis of latent tuberculosis diagnostic antigens.