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提取健康成人血浆中的低密度脂蛋白（ＬＤＬ），与丹参和硝苯吡啶、尼索地平及Ｃｕ透析，分别于透析后２４、４８及７２小时从各组ＬＤＬ中提取脂类进行薄层层析（ＴＬＣ）。结果显示：①ｃｕ可使ＬＤＬ氧化成ｏｘＬＤＬ，ＴＬＣ示ｘ带、游离脂肪酸（ＦＦＡ）、磷脂（ＰＬ）增加，而胆固醇酯（ＣＥ）及甘油三酯（ＴＧ）减少；②钙通道拮抗剂＋Ｃｕ透析与单纯Ｃｕ透析结果相似；③丹参＋Ｃｕ透析的ｘ带显著低于Ｃｕ透析组及钙通道拮抗剂组，且脂质成分与透析前相似。结果表明，Ｘ带可作为脂质过氧化的一个重要指标，丹参具有拮抗ＬＤＬ氧化的作用，这可能是其防治心脑血管病的重要机理之一。
LDL was extracted from plasma of healthy adults, dialyzed with salviae miltiorrhizae, nifedipine, nisoldipine, and Cu, and lipids were extracted from each group of LDL at 24, 48, and 72 hours after dialysis. Analysis (TLC). The results showed that 1cu could oxidize LDL to oxLDL. TLC showed that the x-band, free fatty acid (FFA), phospholipid (PL) increased, while cholesterol ester (CE) and triglyceride (TG) decreased; 2 calcium channel antagonist + Cu dialysis Similar to Cu-only dialysis results;3 The x-band of Danshen+Cu dialysis was significantly lower than that of Cu dialysis group and calcium channel antagonist group, and the lipid composition was similar to that before dialysis. The results showed that X-band can be used as an important index of lipid peroxidation. Salvia miltiorrhiza can antagonize the oxidation of LDL, which may be one of the important mechanisms for the prevention of cardiovascular and cerebrovascular diseases.