（目的）利用病理形态学诊断标准，随访观察胃粘膜异型增生与早期胃癌的关系。（方法）采集该院12年间2800例胃粘膜活检标本，从中检出64例各类型异型增生为随访观察对象。（结果）各类型均可见癌变，但以重度异型增生癌变率高。（结论）轻中度异型增生为可逆性病变，而重度异型增生为不可逆病变或正在癌变中的粘膜变化。 (Objective) To observe the relationship between dysplasia of gastric mucosa and early gastric cancer by using pathological diagnosis criteria. (Methods) A total of 2,800 gastric biopsy specimens were collected from the hospital for 12 years. 64 cases of various types of dysplasia were detected from the hospital as follow-up observation objects. (Results) Carcinogenesis was observed in all types, but the rate of canceration was severe with severe dysplasia. (Conclusion) Mild to moderate dysplasia is a reversible lesion, while severe dysplasia is an irreversible lesion or a mucosal alteration that is undergoing canceration.