采用以前列腺素 F_(2α)为阳性致痛剂,建立大鼠痛经模型、及镜下观察卵巢排卵点等实验方法,验证益母还红丹对动物子宫发育、卵巢排卵及抗痛经的药理作用,并以女宝胶囊为阳性对照品,进行对比观察。结果表明:口服益母还红丹对小鼠子宫发育有一定的促进作用,小鼠卵巢排卵点明显增加,对腹腔注射 PGF_(2α)引起的大鼠在体子宫强烈收缩有显著的缓解作用(P<0.01),并能提高机体非特异性免疫功能,有显著的抗炎、镇痛作用。 Using prostaglandin F_ (2α) as a positive painkiller, the rat model of dysmenorrhea was established, and ovulation test was performed under microscope to verify the pharmacological effects of YM on the development of uterus, ovulation and anti-dysmenorrhea , And female capsule as a positive control, for comparative observation. The results showed that oral YMDH could also promote the development of uterus in mice. The ovulation of mouse ovary increased obviously, which significantly relieved the contraction of rat uterus induced by PGF 2α P <0.01), and can improve the body’s non-specific immune function, a significant anti-inflammatory and analgesic effect.