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从正常妊娠６～８周早期胎盘Ｐｅｒｃｏｌ梯度离心分离出滋养层细胞进行体外培养，观察马鞭草对培养的滋养层细胞形态及绒毛膜促性腺激素（ＨＣＧ）分泌功能的影响，探讨了马鞭草抗早孕的细胞学作用机理。结果表明２５，５０ｍｇ／ｍｌ马鞭草乙醇提取液对滋养层细胞ＨＣＧ分泌有明显的抑制作用，给药后２４ｈ即见部分细胞变圆，４８ｈ大多固缩死亡。一定浓度的马鞭草可直接杀伤滋养层细胞，抑制ＨＣＧ的分泌而中止早孕。
The trophoblast cells were isolated from the placental Percol gradient centrifugation in early pregnancy at 6-8 weeks of normal pregnancy and cultured in vitro. The effects of verbena on the morphology of trophoblast cells and the secretion of chorionic gonadotropin (HCG) were observed. Cytology mechanism of early pregnancy. The results showed that ethanol extract of 25 and 50 mg / ml Verbena had a significant inhibitory effect on the secretion of HCG from trophoblast cells. Some cells became round at 24 h and mostly died after 48 h. A certain concentration of verbena can directly kill trophoblast cells, inhibit the secretion of HCG and stop pregnancy.