重型肝炎是以肝细胞广泛坏死为基础的病理改变,其病情重,发展快,并发症多且病死率高[1],易继发医院感染。据相关文献报道,慢性肝病的医院感染率为23.36%～44.8%[2],而重型肝炎的院内感染率更是高达70%。由此,探讨引起继发医院感染的原因,相关病原学以及如何预防及治疗医院感染从 Hepatitis B is a pathological change based on the extensive necrosis of hepatocytes. It is characterized by severe illness, rapid development, multiple complications and high mortality [1]. It is easy to secondary to nosocomial infection. According to the relevant literature, the prevalence of nosocomial infections in patients with chronic liver disease is 23.36% to 44.8% [2], while the incidence of nosocomial infections in severe hepatitis is as high as 70%. Thus, to explore the causes of secondary nosocomial infections, related etiology and how to prevent and treat nosocomial infections from