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目的:观察不稳定型心绞痛(UAP)患者住院期间的血浆超敏C反应蛋白(hs-CRP)连续变化。方法:选择近期住院治疗的67例UAP患者和稳定型心绞痛患者(对照组)53例,入选对象均于入院后24 h、3 d、7 d和出院前各进行1次血浆hs-CRP检测。结果:UAP组住院期间的不同时间点采样平均血浆hs-CRP浓度值均明显高于对照组(P均<0.05~0.01)。结论:UAP患者住院期间常伴有血浆hs-CRP浓度显著升高,检测后者对心绞痛性质判定有参考意义。
Objective: To observe the continuous changes of plasma hs-CRP during hospitalization in patients with unstable angina pectoris (UAP). Methods: A total of 67 UAP patients and 53 patients with stable angina pectoris (control group) were enrolled in the recent hospitalization. Plasma hs-CRP levels were measured at 24 h, 3 d and 7 d after admission and before discharge. Results: The mean plasma concentrations of hs-CRP in the UAP group at different time points during hospitalization were significantly higher than those in the control group (all P <0.05-0.01). Conclusions: The concentration of hs-CRP in patients with UAP is often accompanied by significant increase in plasma during hospitalization. The detection of the latter has reference significance for the determination of angina pectoris.