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目的了解甘肃省道地产区当归中Mn,Cu,Zn,Mo和Cr的含量,评价其对人体的健康风险。方法在甘肃当归的道地产区选取7个采样点共50份样品,用微波消解—电感耦合等离子体质谱法测定当归中Mn,Cu,Zn,Mo和Cr 5种微量金属元素的含量,并利用健康风险评价模型对其进行健康风险评价。结果当归中Mn,Cu,Zn,Mo和Cr的平均含量分别为24.332 mg/kg,6.105 mg/kg,19.940 mg/kg,0.575 mg/kg和3.370 mg/kg,危害商HQ值的大小为Cr>Mn>Cu>Mo>Zn,危害指数HI<1。结论甘肃省道地产区当归中Mn,Cu,Zn,Mo和Cr这5种微量金属元素的含量对人体健康不存在风险,但是Mn和Cr的日摄入量超出了WHO《药用植物质量控制方法》中的限量规定,故应加以控制。
Objective To understand the contents of Mn, Cu, Zn, Mo and Cr in Angelica of Gansu Province, and to evaluate their health risks to human beings. Methods A total of 50 samples were collected from 7 sampling sites in the real estate area of Danggui of Gansu Province. The contents of trace metal elements Mn, Cu, Zn, Mo and Cr in Angelica sinensis were determined by microwave digestion-inductively coupled plasma mass spectrometry Health risk assessment model for its health risk assessment. Results The average contents of Mn, Cu, Zn, Mo and Cr in Angelica sinensis were 24.332 mg / kg, 6.105 mg / kg, 19.940 mg / kg, 0.575 mg / kg and 3.370 mg / kg, respectively. > Mn> Cu> Mo> Zn, the hazard index HI <1. Conclusion The contents of Mn, Cu, Zn, Mo and Cr in Angelica sinensis in Gansu Province have no risk to human health. However, the daily intake of Mn and Cr is beyond the WHO “quality control of medicinal plants Method ”in the limited provisions, it should be controlled.