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目的探讨肝素钙雾化吸入治疗支气管哮喘的临床意义。方法符合诊断标准的62例患者随机分为常规方法治疗30例(对照组)和常规治疗加用肝素钙雾化吸入32例(治疗组),比较两组治疗后的临床疗效和治疗前后肺功能检查结果,同时监测治疗前后凝血酶原、血小板的变化。结果治疗组临床症状缓解明显,总有效率93.75%,对照组70%,治疗组PEF预计值(%)治疗前(71.98±1.21),治疗后(81.92±1.80),前后有显著差别,对照组无明显变化。治疗组在治疗过程中及治疗后未出现明显不良反应,凝血试验未见异常变化。结论肝素钙雾化吸入治疗支气管哮喘疗效好,肺功能改善明显。
Objective To investigate the clinical significance of heparin calcium nebulization in the treatment of bronchial asthma. Methods According to the diagnostic criteria, 62 patients were randomly divided into routine treatment of 30 cases (control group) and conventional therapy plus heparin calcium inhalation in 32 cases (treatment group). The clinical efficacy and the pulmonary function before and after treatment were compared between the two groups Check the results, while monitoring prothrombin time before and after treatment, changes in platelets. Results The clinical symptoms of the treatment group were relieved obviously. The total effective rate was 93.75%, while the control group was 70%. The predicted value of PEF in the treatment group was 71.98 ± 1.21 before treatment and 81.92 ± 1.80 after the treatment, No significant changes. No significant adverse reactions were found in the treatment group during and after treatment, and no abnormal changes were found in the coagulation tests. Conclusion Heparin calcium atomization inhalation treatment of bronchial asthma good effect, significant improvement in lung function.