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检测肝硬化病人硒的浓度 ,探讨肝硬化程度及自发性细菌性腹膜炎时对血清及腹水中硒浓度的影响。对 32例肝硬化病人及 1 0例健康人血清及腹水中硒浓度进行检测。病人分为 4组 , 组为对照 ( 1 0例 ) , 组为肝硬化代偿期 ( 1 6例 ) , 组为肝硬化合并大量腹水 ( 1 4例 ) , 组为大量腹水自发性细菌性腹膜炎 ( 1 3例 ) ( SBP)。用 939AA光谱测定仪 - Unicam VP99蒸发系统通过原子吸收光谱分光光度法检测血清中硒浓度。研究结果显示 ,与对照组相比 ,所有肝硬化病人血清中硒浓度均明显下降 ( P <0 .0 5 )。代偿期肝硬化病人 ( 组 )比其它两组( 、 组 )病人血清中硒浓度更高 ,但无统计学意义 ( P >0 .0 5 ) ,肝硬化失代偿的两组病人不论有无自发性腹膜炎 ( 、 组 )腹水硒浓度无差异。结论为 ,肝硬化病人血清硒浓度降低 ,硒浓度下降与肝硬化程度及 SBP无关
To detect the concentration of selenium in patients with cirrhosis and to explore the extent of cirrhosis and spontaneous bacterial peritonitis on serum and ascites concentration of selenium. Selenium concentrations in serum and ascites of 32 patients with cirrhosis and 10 healthy controls were detected. Patients were divided into 4 groups, the control group (10 cases), the group of decompensated cirrhosis (16 cases), the group of cirrhosis combined with large amounts of ascites (14 cases), the group of spontaneous bacterial peritonitis (13 cases) (SBP). Selenium concentrations in serum were determined by atomic absorption spectrophotometry using a 939AA spectrometer - Unicam VP99 evaporation system. The results showed that serum selenium levels were significantly decreased in all cirrhotic patients compared with the control group (P <0.05). Patients with decompensated cirrhosis (sera) had higher serum selenium concentrations than those of the other two groups (p <0.05), and patients with decompensated cirrhosis did not have statistical significance No spontaneous peritonitis (group) no difference in selenium concentration. Conclusions: Serum selenium levels decreased in patients with cirrhosis, and selenium levels were not associated with cirrhosis and SBP