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目的 探索尿道下裂术后的再造尿道易于感染的原因、感染源及细菌种类 ;据此改进围手术期处理措施 ,以降低感染率。方法 应用细菌培养鉴定、基因分型鉴定等从分子水平证实细菌的来源及种类。结果 经尿道外口逆行进入和再造尿道材料携带是细菌主要来源。引起尿道下裂感染主要是革兰氏阳性球菌。最有效抗生素是去甲万古霉素。结论 尿道下裂术后感染是切口感染而不是泌尿系感染。再造尿道感染率高于皮肤 (黏膜 )的原因在于造成了比体表更适合细菌生长繁殖的微环境。
Objective To explore the causes of urethra re-infection after urethral hypospadias, the source of infection and the type of bacteria, and to improve perioperative management to reduce the infection rate. Methods Bacterial culture identification and genotyping were used to confirm the origin and types of bacteria at the molecular level. Results Retrograde transurethral urethral catheterization was the main source of bacteria. Cause hypospadias infection is mainly gram-positive cocci. The most effective antibiotic is norvancomycin. Conclusions Postoperative hypospadias infection is incisional infection rather than urinary tract infection. Reproduction of urinary tract infection rate higher than the skin (mucosa) is due to create a more suitable for the growth and reproduction of bacteria than the surface microenvironment.