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在南北美轻度到重度地方性甲状腺肺肿地区和非地方病城市地区内,测定了新生儿脐带血的 T_4、T_3、rT_3、和 TSH 值。发现在南美城市地区居住的新生儿较居住在加拿大的新生儿 rT_3浓度显著偏高。在所研究的两组新生儿中,各种甲状腺参数当中没有不同。患甲状腺肿母亲的血液中 T_3和TSH 浓度明显地高于非甲状腺肿母亲的血液中 T_3和 TSH 的浓度,然而这些变化并不影响在胎儿循环中的甲状腺激素、rT_3或 TSH 浓度.
T_4, T_3, rT_3, and TSH values of neonatal umbilical cord blood were measured in mild to severe endemic thyroid lungs and non-endemic urban areas in North and South America. Newborns living in urban areas in South America were found to have significantly higher rT_3 concentrations than neonates living in Canada. Of the two groups of newborns studied, there was no difference among the various thyroid parameters. T_3 and TSH concentrations in the blood of goiter mothers were significantly higher than those of non-goat mothers, however, these changes did not affect thyroid hormone, rT_3 or TSH concentrations in the fetal circulation.