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目的回顾性分析妊娠期高血压疾病住院患者的用药情况,分析其用药合理性。方法收集该医院产科2011年1月至2015年6月主要诊断为妊娠期高血压疾病的住院患者基本资料、用药信息和费用信息,用SPSS22.0软件对数据进行统计分析。结果共纳入妊娠期高血压疾病住院患者974例,其中,重度子痫前期患者最多,占38.81%(378/974例)。对使用药物进行分析,共包括降压药物4种、防治子痫药物3种、镇静药物3种、利尿剂、纠正低蛋白血症药物和中成药各1种。各亚组用药情况略有差异。使用频次前10位的药品为维生素C、维生素E、硝苯地平、川芎嗪、硫酸镁、硝苯地平缓释片、白蛋白、地西泮片、乌拉地尔和呋塞米。结论妊娠期高血压疾病住院患者的药物治疗是以防治子痫前期和降压为主,同时中成药川芎嗪联合使用,符合疾病诊疗指南用药要求,用药基本合理。但维生素C和维生素E的使用存在争议。
Objective To retrospectively analyze the medication situation of inpatients with hypertensive disorder complicating pregnancy and analyze its rationality. Methods From January 2011 to June 2015, we collected the basic information, medication information and cost information of inpatients with gestational hypertension who were mainly diagnosed as gestational hypertension in our hospital from January 2011 to June 2015. SPSS22.0 software was used to analyze the data. Results A total of 974 in-patients with hypertensive disorder complicating pregnancy were included. Among them, the patients with severe preeclampsia accounted for 38.81% (378/974 cases). Analysis of the use of drugs, including a total of 4 kinds of antihypertensive drugs, anti-eclampsia drugs 3, sedatives 3, diuretics, hypoproteinemia and Chinese medicine correct one. The sub-group medication slightly different situation. The top 10 drugs used were vitamin C, vitamin E, nifedipine, ligustrazine, magnesium sulfate, nifedipine sustained release tablets, albumin, diazepam tablets, urapidil and furosemide. Conclusion The drug treatment of hospitalized patients with hypertensive disorder complicating pregnancy is based on the prevention and treatment of preeclampsia and antihypertensive drugs. At the same time, the Chinese patent medicine Ligustrazine is used in combination with the drug requirements of the guidelines for diagnosis and treatment of diseases, and the medication is basically rational. However, the use of vitamin C and vitamin E is controversial.