凡具有手性的合成药和半合成药,多数是外消旋体。一般而言,药物的光学异构体,在药动学和药效学方面总是存在着差别。近来立体异构影响药物的作用和处置已经引起人们关注。本文评述一些手性来自分子中不对称碳原子的药物,在处置和疗效方面的对映体选择性,以及有关的影响因素。口服吸收 Where there is chiral synthetic drugs and semi-synthetic drugs, mostly racemic. In general, the optical isomers of drugs always differ in pharmacokinetics and pharmacodynamics. Recently, the role of stereoisomerism drugs and disposal have drawn people’s attention. This article reviews the chirality of drugs derived from asymmetric carbon atoms in molecules, their enantioselectivity in treatment and efficacy, and their associated factors. Oral absorption