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对源于干细胞的淋巴细胞,通过各种免疫学技术明确了T 细胞和B 细胞分化过程,这一结果给淋巴细胞系肿瘤的分类带来了根本性的变化。目前,T 细胞和B 细胞根据其各自的功能分为多种亚目或亚类,源于干细胞分化过程中的细胞均有其各自不同的特征。这些细胞的肿瘤化,可以理解为在各自不同的分化阶段上失去了分化机能克隆的增殖,或显示异常分化的增殖细胞群。这很象神经母细胞瘤的形成过程。与神经母细胞瘤不同的是,淋巴细胞的功
For stem cell-derived lymphocytes, the differentiation of T cells and B cells is clarified through various immunological techniques, a result that has led to fundamental changes in the classification of lymphoid lineages. At present, T cells and B cells are divided into various subtypes or subclasses according to their respective functions. Cells derived from stem cell differentiation have their own different characteristics. The tumorigenesis of these cells can be understood as a loss of proliferation of differentiating functional clones at each respective stage of differentiation or a population of proliferating cells that show abnormal differentiation. This is very much like the formation of neuroblastoma. Unlike neuroblastoma, lymphocyte work