论文部分内容阅读
目的:评价中药促进术后恢复方案(中药ER AS)在直肠癌保肛术中的疗效和安全性。方法:以符合入组条件的70例直肠癌手术患者为研究对象,随机分成中药ER AS组和对照组。中药ER AS组术后在常规ER AS的基础上予通腑益气活血法中药治疗,对照组采用传统围手术期处理方法,待肠道自然恢复。观察2组患者术后应激指标白细胞介素(IL)-10、C反应蛋白(CR P)及肿瘤坏死因子(TNF)、胃肠功能恢复、并发症以及术后住院时间等。结果:治疗第3、7天,2组IL-10、TNF、CR P分别比较,差异均有非常显著性意义(P<0.01)。中药ER AS组与对照组比较,首次排气、排便时间提前(P<0.01),更早地进食流质、半流质(P<0.01),总并发症发生率降低(P<0.05),术后住院时间缩短(P<0.01)以及术后住院费用减少(P<0.01)。但2组患者的感染率和非感染性并发症发生率比较,差异均无显著性意义(P>0.05)。结论:中药ER AS在直肠癌保肛手术中的应用安全有效,患者术后胃肠功能恢复加快,总并发症发生率降低,术后住院时间缩短,术后住院费用降低,具有较好的临床效果,值得进一步研究推广。
Objective: To evaluate the efficacy and safety of traditional Chinese medicine in promoting postoperative recovery (traditional Chinese medicine ER AS) in rectal cancer preservation of the anus. Methods: A total of 70 patients with rectal cancer who met the criteria of admission were randomly divided into two groups: ER AS group and control group. The traditional Chinese medicine ER AS group was treated with traditional Chinese medicine (TCM) on the basis of conventional ER AS and the traditional perioperative management method in the control group until the intestine was naturally recovered. The postoperative stress indexes IL-10, CRP and TNF, gastrointestinal function recovery, complications and postoperative hospital stay were observed in the two groups. Results: The difference of IL-10, TNF and CRP between the two groups on the 3rd and 7th day of treatment was significant (P <0.01). Compared with the control group, the time of first excretion and defecation was earlier (P <0.01), and the rate of total complication was lower (P <0.05) Shorter hospital stay (P <0.01), and lower postoperative hospitalization costs (P <0.01). However, there was no significant difference between the two groups in the incidence of infection and non-infectious complications (P> 0.05). Conclusion: The application of traditional Chinese medicine ER AS in anorectal surgery of rectal cancer is safe and effective. The postoperative recovery of gastrointestinal function is accelerated, the total complication rate is decreased, the postoperative hospitalization time is shortened, the postoperative hospitalization cost is reduced, and the clinical application of ER AS is better Effect, it is worth further study and promotion.