用国产人绝经后促性腺激素(human menopausal gonadotropin,简称hMG),治疗下丘脑-垂体功能障碍引起的闭经、月经稀少和不育患者23例,共35周期的经验。以B型超声诊断仪检查和宫颈粘液评分作为主要监护。结果:23例35个治疗周期中,32个周期有排卵,13例妊娠,其中7例单胎;3例双胎;2倒流产;1例宫外孕。3例发生卵巢过度刺激综合征(ovarian hyperstimulation syndrome,简称OHSS)。对hMG的疗效及并发症加以讨论。 With domestic human menopausal gonadotropin (human menopausal gonadotropin, referred to as hMG), the treatment of hypothalamic - pituitary dysfunction caused by amenorrhea, menorrhagia and infertility in 23 patients, a total of 35 cycles of experience. B-type ultrasound examination and cervical mucus score as the main guard. Results: Twenty-three of the 35 treatment cycles had ovulation in 32 cycles and 13 pregnancies, of which 7 were singletons, 3 were twins, 2 were aborted, and 1 was ectopic. 3 cases of ovarian hyperstimulation syndrome (OHSS). The efficacy and complications of hMG are discussed.