Supramolecular synthesis of 3,4-dihydropyrimidine-2(1H)-one/thiones under neat conditions

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An efficient solvent free method for the synthesis of various 3,4-dihydropyrimidin-2(1H)-one/thiones in excellent yields using sulfonated β-cyclodextrine as recyclable catalyst is described. Sulfonated β-cyclodextrine was found to be efficient, recyclable heterogeneous catalyst and showed rate enhancements, high yields and short reaction times in this transformation.
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