论文部分内容阅读
目的:观察云克联合益肾强督汤治疗强直性脊柱炎的疗效。方法:将102例患者随机分为2组,治疗组71例采用云克联合中药益肾强督汤治疗,对照组31例采用益肾强督汤治疗。观察全身痛程度、脊柱痛程度、晨僵持续时间、医生总体评价等疗效评价指标以及药物不良反应情况。结果:临床疗效总有效率治疗组为95.77%,明显高于对照组(80.65%),差异有显著性意义(P<0.05)。治疗组全身痛Likert四级评分、指地距、胸廓活动度、Schober征、脊柱活动度、“4”字试验等指标均较治疗前改善,差异有显著性或非常显著性意义(P<0.05,P<0.01);治疗后2组全身痛Likert四级评分等各指标比较,差异均有显著性意义(P<0.05)。治疗后治疗组血沉、C反应蛋白、谷丙转氨酶均较治疗前改善,差异有显著性或非常显著性意义(P<0.05,P<0.01);治疗后2组血沉、C反应蛋白、谷丙转氨酶比较,差异均有显著性意义(P<0.05)。结论:云克联合益肾强督汤治疗强直性脊柱炎,疗效显著,值得推广。
Objective: To observe the efficacy of Yunke combined with Yishen Qiangsu Tang in treating ankylosing spondylitis. Methods: 102 patients were randomly divided into two groups. The treatment group (n = 71) was treated with Yunke Qiangdu Decoction. The control group (n = 31) was treated with Yishen Qiangsu Decoction. To observe the degree of systemic pain, spinal pain, morning stiffness duration, the overall evaluation of the doctor and other indicators of efficacy evaluation and adverse drug reactions. Results: The total effective rate of the clinical treatment group was 95.77%, which was significantly higher than that of the control group (80.65%), the difference was significant (P <0.05). The treatment group had similar scores of Likert four-grade score, referring to the distance from the ground, the activity of the thorax, the Schober sign, the activity of the spine, the “4” word test and other indicators were better than before treatment, the difference was significant or very significant <0.05, P <0.01). There were significant differences between the two groups in the Likert four-grade score after treatment (P <0.05). After treatment, the levels of ESR, C-reactive protein and alanine aminotransferase in treatment group were improved compared with before treatment, the difference was significant or very significant (P <0.05, P <0.01); after treatment, the two groups of ESR, C-reactive protein, Aminotransferase comparison, the difference was significant (P <0.05). Conclusion: Yunke combined Yishen Qiangsu Tang treatment of ankylosing spondylitis, significant effect, it is worth promoting.