心脑血管疾病已成为严重危害人类健康的第一杀手,而动脉粥样硬化(ＡＳ)是心脏病和中风的主要病因,胆固醇在动脉粥样硬化中的重要作用业已被普遍认可。在正常情况下,大部分胆固醇是细胞壁的结构成分,其余的胆固醇则通过血流运至肝脏、肾上腺、卵巢、睾丸和皮肤等器官,被合成为胆 Cardiovascular disease has become the first killer of serious harm to human health, and atherosclerosis (AS) is the leading cause of heart disease and stroke. The important role of cholesterol in atherosclerosis has been generally recognized. Under normal circumstances, the majority of cholesterol is the structural component of the cell wall, and the remaining cholesterol is transported to the liver, adrenal glands, ovaries, testes and skin and other organs by blood flow, was synthesized as gallbladder