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通过分析燃煤型砷中毒病区人群尿总砷(Tot- As) 、尿无机砷(In - As) 、无机砷/ 总砷比值(In - As/Tot- As) 和发砷以及相关因素对病情的影响,发现患者体内砷负荷的累积性增加及机体解毒能力的逐渐下降可能是砷中毒病情逐渐加重的原因之一。病区居民长期燃用高砷煤致空气、食品严重污染以及改灶措施不彻底,是导致新发病人不断出现、病情继续发展及皮肤癌逐渐增加的原因。研究初步揭示砷中毒患者无机砷代谢研究的必要性,并对砷中毒综合防治措施提出建议。
Based on the analysis of Tot-As, In-As, In-As / Tot-As and related arsenic in coal-burning arsenism patients, It is found that the cumulative increase of arsenic load and the gradual decline of the body’s detoxification ability may be one of the reasons for the aggravating arsenicosis. Long-term burning of ward residents with high-arsenic-induced air, serious food contamination and the stove is not complete, is leading to the emergence of new patients, the disease continues to develop and the reasons for the gradual increase in skin cancer. The study initially revealed the necessity of studying inorganic arsenic metabolism in arsenic poisoning patients, and put forward suggestions for the comprehensive prevention and control measures of arsenic poisoning.