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目的观察中西医结合治疗慢性肾小球肾炎(CGN)的临床疗效。方法采用随机对照的临床研究方法,观察中西医结合疗法对40例CGN患者的临床疗效和24h尿蛋白定量、肌酐和尿素氮等的变化,并与40例单纯西医治疗对照组进行比较。结果观察组40例,完全缓解12例(30%),基本缓解13例(32.5%),好转10例(25%),无效5例(12.5%),总有效率87.5%。对照组40例,完全缓解6例(15%),基本缓解7例(17.5%),好转10例(25%),无效17例(42.5%),总有效率57.5%。两组总有效率比较,观察组明显高于对照组,经统计学处理差异有统计学意义(P<0.01)。结论中西医结合治疗CGN较单纯西医治疗临床疗效好。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of chronic glomerulonephritis (CGN). Methods A randomized controlled clinical study was conducted to observe the clinical curative effect of 40 cases of CGN patients and the changes of 24 h urinary protein, creatinine and urea nitrogen in TCM-WM combination therapy and compared with 40 western medicine-only control groups. Results In the observation group of 40 cases, complete remission was achieved in 12 cases (30%), complete remission in 13 cases (32.5%), improvement in 10 cases (25%), ineffective in 5 cases (12.5%) and total effective rate in 87.5%. The control group of 40 cases, 6 cases (15%) were completely relieved, 7 cases (17.5%) were basically relieved, 10 cases (25%) were improved, 17 cases (42.5%) were ineffective and the total effective rate was 57.5%. The total effective rate of two groups, the observation group was significantly higher than the control group, the statistical difference was statistically significant (P <0.01). Conclusion The treatment of CGN with traditional Chinese and Western medicine is better than Western medicine alone.