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本文对HBsAg持续阳性104例;HBsAg阴性1646例追踪观察25年.恶性肿瘤的发病率分别是25％和4.13％,两 者差异显著(P<0.05).同时现察到HBsAg阳性组原发性肝癌(PHC)发病率(10.5％)也明显高于对照组(0.36％).提示HBV感染除了 和PHC有密切关系外,也是易患其它类型恶性肿瘤的高危人群.
In this paper, 104 cases of persistent HBsAg positive and 1646 cases of HBsAg-negative follow-up observation of 25 years.The incidence of malignant tumors were 25% and 4.13%, the difference was significant (P <0.05) The incidence of PHC (10.5%) was also significantly higher than that of the control group (0.36%), suggesting that HBV infection is also a high risk group with other types of malignancies besides PHC.