论文部分内容阅读
目的 探讨儿童慢性咳嗽与慢性鼻窦炎的关系。方法 对咳嗽时间 1个月以上的 1 0 6例 2～ 1 4岁儿童作临床观察 ,根据鼻窦片、胸片、螨尘皮试、支气管扩张试验及疗效 ,将其分为鼻窦炎组 2 1例 ,鼻窦炎合并咳嗽变异性哮喘 (CVA) 2 1例 ,CVA或哮喘 4 4例 ,支气管炎等 2 0例。同时做诱导痰细胞学检查。结果 慢性咳嗽儿童中 3 9 6% ( 42 / 1 0 6)有慢性鼻窦炎 ;鼻窦炎合并CVA组与CVA或哮喘组相似 ,螨皮试阳性率和支气管扩张试验的阳性率均达 4 0 %左右 ,诱导痰嗜酸粒细胞、肥大细胞含量增高 ,与单纯鼻窦炎组显著不同。结论 上下呼吸道是一个整体 ,对儿童慢性咳嗽应注意鼻窦炎的伴发 ,而过敏原皮试阳性、支气管扩张试验阳性及诱导痰嗜酸粒细胞和 (或 )肥大细胞增多是CVA或哮喘的有力证据。
Objective To explore the relationship between chronic cough and chronic sinusitis in children. Methods One hundred and six cases of children aged 2-4 years old with coughing time of more than 1 month were studied clinically. According to the sinuses, chest radiograph, mite skin test, bronchodilator test and curative effect, they were divided into sinusitis group 21 Cases, sinusitis with cough variant asthma (CVA) 21 cases, CVA or asthma in 44 cases, such as bronchitis 20 cases. At the same time do induced sputum cytology. Results Cough sinusitis was found in 396% (42/106) of children with chronic cough; sinusitis with CVA group was similar to CVA or asthma group, the positive rate of mite skin test and bronchodilator test were 40% Induced sputum eosinophils, mast cells increased, significantly different from the group of simple sinusitis. Conclusion The upper and lower respiratory tract as a whole, should pay attention to chronic sinusitis associated with chronic cough in children, and skin test positive allergen, bronchodilator test positive and induced sputum eosinophils and (or) mast cells is strong evidence of CVA or asthma .