自然杀伤细胞(NK)是单个核白细胞,它能杀伤某些其他细胞,尤其是某些肿瘤细胞,因而它可构成机体防御肿瘤的前线。根据全部或绝大多数NK细胞的活性,认为它是一个同T和B淋巴细胞完全不同的大颗粒淋巴细胞群(LGL)。虽然最近几年对NK的活性进行了广泛地研究,但仍然难以描述NK细胞的特点。从表面标志来看,NK细胞和LGL细胞似乎是异源的。多数LGL都具有FcrR、Ia抗原以及用单克降抗体OKM1检出的抗原。为了查清这种可能 Natural killer (NK) cells are mononuclear leukocytes, which kill certain other cells, especially certain tumor cells, so they can form the body’s front line against tumors. Based on the activity of all or most NK cells, it is thought to be a completely different large granulocyte population (LGL) from T and B lymphocytes. Although NK activity has been extensively studied in recent years, it is still difficult to characterize NK cells. From surface markers, NK cells and LGL cells appear to be heterologous. Most LGL have FcrR, Ia antigens and antigen detected with the monoclonal antibody OKM1. In order to find out this possibility